― The Edge Of America (Dee the Lurker), Friday, 19 August 2005 08:34 (nineteen years ago) link
― johnsmith, Friday, 26 August 2005 13:46 (nineteen years ago) link
― anthony, Friday, 26 August 2005 13:47 (nineteen years ago) link
― p.j. (Henry), Friday, 26 August 2005 13:52 (nineteen years ago) link
― Maria :D (Maria D.), Friday, 26 August 2005 14:01 (nineteen years ago) link
― barbarianuser, Friday, 26 August 2005 14:02 (nineteen years ago) link
― Colonel Poo (Colonel Poo), Friday, 26 August 2005 14:03 (nineteen years ago) link
― roxymuzak (roxymuzak), Friday, 26 August 2005 14:03 (nineteen years ago) link
― ken c (ken c), Friday, 26 August 2005 14:06 (nineteen years ago) link
― stelf)xxxxxx, Friday, 26 August 2005 14:07 (nineteen years ago) link
― Barnaby (Barnaby), Friday, 26 August 2005 15:51 (nineteen years ago) link
― M. White (Miguelito), Friday, 26 August 2005 15:55 (nineteen years ago) link
― grimly fiendish (grimlord), Friday, 26 August 2005 15:58 (nineteen years ago) link
― TBA (TBA), Friday, 26 August 2005 19:56 (nineteen years ago) link
― Tripmaker (SDWitzm), Friday, 26 August 2005 20:03 (nineteen years ago) link
― gear (gear), Friday, 26 August 2005 20:37 (nineteen years ago) link
The term "Fourth World" has often been used to describe various ethno-electronic compositions. Joining trumpeter Jon Hassell in different combinations on Possible Musics are coproducer and synthesist Brian Eno and percussionists Nana Vasconcelos and Ayibe Dieng, among others. Hassell has found a unique way to summon a lush, otherworldly sound from his trumpet, applying the Indian vocal techniques he learned from Pandit Pran Nath to the way he plays his instrument. On Possible Musics, he mixes his ethereal brass sounds with hand percussion, bass, analog synths, Eno's trademark studio treatments, and the occasional looped trumpet or keyboard riff. The hypnotic fusion of Indian and African aesthetics creates a dreamy brand of otherworldly world music that, despite the electronic influences swirling around it, maintains a strongly organic feel. This classic recording predated all of the ethnoambient music that proliferated throughout the last decade, but unlike many of those efforts, it still retains a strong sense of identity
― gear (gear), Friday, 26 August 2005 20:38 (nineteen years ago) link
― kelsey (kelstarry), Friday, 26 August 2005 20:52 (nineteen years ago) link
― Ronan (Ronan), Friday, 26 August 2005 20:52 (nineteen years ago) link
― Crackity (Crackity Jones), Friday, 26 August 2005 22:29 (nineteen years ago) link
― Onimo (GerryNemo), Friday, 26 August 2005 23:00 (nineteen years ago) link
― Leeeeeeee (Leee), Friday, 26 August 2005 23:14 (nineteen years ago) link
― melton mowbray (adr), Saturday, 27 August 2005 03:05 (nineteen years ago) link
― Hurting (Hurting), Saturday, 27 August 2005 03:11 (nineteen years ago) link
― dan m (OutDatWay), Saturday, 27 August 2005 03:21 (nineteen years ago) link
― milozauckerman (miloaukerman), Saturday, 27 August 2005 03:23 (nineteen years ago) link
― Oh Lord, My God, is there no help for the widow's son? / Kate (papa november), Saturday, 27 August 2005 03:25 (nineteen years ago) link
-- ---- (--...) (webmail), August 27th, 2005 1:22 AM. (later) (link)
― Alec in NYC (ex machina), Saturday, 27 August 2005 04:26 (nineteen years ago) link
― morris garage (Jody Beth Rosen), Saturday, 27 August 2005 05:31 (nineteen years ago) link
― jimmy glass (electricsound), Saturday, 27 August 2005 05:34 (nineteen years ago) link
On August 2, 2005, WENN ran a story entitled "Hatcher Shocks Neighbors with Passion Sex Wagon," which claimed Teri Hatcher had "amorous encounters" with men in a van parked outside her home. Originally published in The Sun newspapers in the UK, WENN has been informed by by Ms. Hatcher's legal representatives that the story has no basis whatsoever in truth. According to WENN's official statement, "WENN retracts this story and apologies (sic) unreservedly to Ms. Hatcher."
― Rickey Wright (Rrrickey), Saturday, 27 August 2005 08:46 (nineteen years ago) link
― Trayce (trayce), Saturday, 27 August 2005 08:54 (nineteen years ago) link
― my name is john. i reside in chicago. (frankE), Saturday, 27 August 2005 15:08 (nineteen years ago) link
― Rock Hardy (Rock Hardy), Saturday, 27 August 2005 15:11 (nineteen years ago) link
― Dom Passantino (Dom Passantino), Saturday, 27 August 2005 15:12 (nineteen years ago) link
― firstworldman (firstworldman), Saturday, 27 August 2005 23:29 (nineteen years ago) link
― Josh in Chicago (Josh in Chicago), Saturday, 27 August 2005 23:33 (nineteen years ago) link
― ath (ath), Sunday, 28 August 2005 03:59 (nineteen years ago) link
-- gypsy mothra (meet...), August 26th, 2005. (gypsy mothra) (later)
-- Forest Pines (il...), August 26th, 2005 12:26 AM.
― Wiggy (Wiggy), Sunday, 28 August 2005 04:29 (nineteen years ago) link
― gem (trisk), Sunday, 28 August 2005 07:59 (nineteen years ago) link
Dear BlogBlogs are the newest way to get yourself “out there”, whether it be to express opinion, express anger, or express talent. Blogs are surely taking over the “vanity webpage/html” and becoming a new form of addiction for online hobbyists. The article, “The Blog Phenomenon” written by John C. Dvorak, published by PC Magazine on February 26th, 2002, Dvorak clearly states that the uprising of the “blog: a public online diary”, and the decrease of the typical webpage and/or HTML. The convenience of the blog is almost the same as the addiction-editing a blog is so much easier, as is making the actual appearance of the blog more attractive, but the blog is also addicting because it is a need to keep-up the blog’s contstant change in content and appearance. Dvorak offers ideas he believes the be the main reasons to the addiction of the blog, which are all either social, personal, mental, or talent-related problems. The blog is a way to to express/alleviate one-self through posting, and allows the content much freedom, but compels the blogger to constantly update.“The blog is the latest way to announce to the world: I am here. My thouhgts and my doings are interesting to the rest of the world.”, this qoute is the main reason stated for the evergoing continuation of the “blog”. The word “blog” itself came from “WeB log”, and the main promoting website, pyra.com, switched the their name to “blog”, there enforcing the new websites name, www.blogger.com, and if you used this, you were a “blogger”! The blogs can even be searched at www.blogfinder.com for interesting material, or whatever your fancy may be. The author believes the audiences should admit that blogs are much more interesting than the typical “vanity site”. The blog is believed to be better than the “sloppy HTML”, and the material must alwuas be kept current. Bloggers even apologize when their material isn’t up to date, “as if anyone cares”. If you ask an avid blogger why they blog, they will respond with, “because it’s fun” or “because it’s easy”, but Dvorak believes there are more specific reason deep within the blogger for the need to blog.The possibilities of Dvorak’s reasoning for blogging range anywhere from personal, to mental, and to a wishing to be graced for their talent in writing. His first reason for blogging, although he thinks it is “the least likely, since it is too trite and shallow” is “Ego Gratification: need to be the center of attention.” His next excuse to blog is “Antidepersonalization”, when people think they are so normal and bland, the need a way to set themselves apart from the rest. His third possibility for the act of the blog, is to relieve yourself of everyday problems and frustration, or “Elimination of Frustration.” Another reason to blog is the general “societal need to share”...some actually enjoy sharing their ideas and thoughts. Dovark’s last excuse to blog is the “wanna-be writer”, the writer that craves to be published-and a blog allows you to do so without depending on anyone but yourself. Dvorak leaves the article with stating the main reason for the blog is still unclear, and he is content with knowing that his pet peeve of bloated cat pictures on normal websites, have decreased since the more convenient and random, publically personal, “blog:”
― Kiel Pratt, Tuesday, 30 August 2005 05:38 (nineteen years ago) link
― Dan I. (Dan I.), Tuesday, 30 August 2005 05:43 (nineteen years ago) link
Preliminary analysis suggests CX717, when compared to placebo, increased wakefulness in a dose-related manner and improved performance of those subjects that were impaired
Irvine, CA (May 2, 2005) - Cortex Pharmaceuticals, Inc. (AMEX: COR) announced that preliminary analysis suggests that CX717, when compared to placebo, increased wakefulness in a dose-related manner and improved performance in healthy male subjects that became impaired during 27 hours without sleep. The study was performed in the United Kingdom at the Academic Clinic for Disorders of Sleep and Wakefulness within the Human Psychopharmacology Research Unit at the Medical Research Centre, School of Biomedical and Molecular Sciences, University of Surrey by Dr. Julia Boyle, Acting Director of the Research Unit and Professor Anthony N. Nicholson, Medical Director and Visiting Professor of Aviation Medicine, King’s College London.
According to Dr. Boyle, “There is evidence that it is the low levels of performance in individuals particularly affected by sleep deprivation that are alleviated by CX717, and that this effect is seen with many measures of performance and across the whole dose range studied from 100 mg through 300 mg to 1000 mg.?E
Professor Anthony N. Nicholson, a clinical neuroscientist who specialises in the pharmacology of the sleep-wakefulness continuum, said “We found that all the three doses of CX717 had an alerting effect in subjects deprived of sleep overnight. With the 100 mg dose there was evidence of increased wakefulness overnight, but an alerting effect was not seen during the recovery sleep the following morning. With both the 300 mg and 1000 mg doses the overnight alerting effect extended well into the next day recovery sleep, and the effect was greater with the higher dose. These findings, and the studies on performance, indicate clearly that the alerting effects and the duration of the alerting effects of CX717 are dose related?E
In the study, 16 young healthy men were administered three different doses of CX717 and a placebo control in a randomized, double-blind, four-way crossover design. All subjects were sleep deprived for 27 hours during which time they were tested on measures of memory, attention, vigilance, reaction time, and executive function. Propensity to fall sleep was measured with a modified wakefulness test given at 4 AM on the night of testing. The integrity of recovery sleep was assessed by polysomnography.
Dr. Roger Stoll, Cortex’s Chairman, President & CEO, stated “the results from this study are very encouraging and begin to validate our AMPAKINE pharmacology in humans. This study supports our development approach for CX717. We plan to conduct pilot studies in variety of brain disorders that might benefit from AMPAKINE pharmacology including Alzheimer’s Disease, Attention Deficit Hyperactivity Disorder (ADHD), and sleep disorders.?E
Cortex believes Ampakine compounds could selectively increase cerebral arousal without increasing somatic arousal and may prove useful for improving performance and decreasing the excessive daytime somnolence associated with shift work, narcolepsy and other conditions caused by sleep deprivation. Narcolepsy is an Orphan Drug indication, which could reduce both the cost and time to market for a potential therapeutic agent from Cortex.
About excessive daytime somnolence (EDS)The National Commission on Sleep Disorders estimates that 40 million Americans are either chronically or intermittently affected with various sleep disorders. In addition to the tremendous personal pain and suffering they inflict, sleep disorders are a tremendous drain on the productivity and safety of our country: falling asleep at the wheel is one of the most costly and devastating problems on American highways; accidents in the workplace due to sleep deprivation are commonplace and damaging to industry; the annual direct cost to society is over $15 billion. Ampakine products may also be useful in the treatment of a variety of sleep disorders associated with EDS including narcolepsy, jet lag and shift work sleep disorder.
― J-rock (Julien Sandiford), Tuesday, 30 August 2005 05:45 (nineteen years ago) link
― Ste (Fuzzy), Tuesday, 30 August 2005 08:17 (nineteen years ago) link
― Markelby (Mark C), Tuesday, 30 August 2005 09:09 (nineteen years ago) link
Period Ending: 12/31/2004 12/31/2003 12/31/2002 12/31/2001 Liquidity Ratios Current Ratio n/a n/a n/a n/a Quick Ratio n/a n/a n/a n/a Cash Ratio n/a n/a n/a n/a Profitability Ratios Gross Margin 92% 92% 90% 82% Operating Margin 32% 31% 34% 18% Pre-Tax Margin 28% 27% 29% 8% Profit Margin 19% 17% 18% 5% Pre-Tax ROE 23% 24% 27% 10% After Tax ROE 16% 15% 17% 6%
― Lupton Pitman (Chris V), Tuesday, 30 August 2005 12:05 (nineteen years ago) link
― RJG (RJG), Tuesday, 30 August 2005 12:09 (nineteen years ago) link
― Ed (dali), Tuesday, 30 August 2005 12:10 (nineteen years ago) link
― mark grout (mark grout), Tuesday, 30 August 2005 12:11 (nineteen years ago) link
― aldo_cowpat (aldo_cowpat), Tuesday, 30 August 2005 12:11 (nineteen years ago) link