Bloomberg: Astra Vaccine’s 90% Efficacy in Covid Came in Younger Group
The dose of AstraZeneca Plc’s Covid vaccine that showed the highest level of effectiveness was tested in a younger population than a bigger dose that showed less efficacy, according to the head of the U.S. Operation Warp Speed program.The vaccine being developed with Oxford University was 90% effective when a half-dose was given before a full-dose booster, the partners said on Monday. However, that regime was administered to participants in a group whose age was capped at 55, Warp Speed’s Moncef Slaoui said Tuesday in a phone call with reporters.Researchers have been puzzling about the AstraZeneca report since it was released, wondering why a smaller dose of the vaccine might have appeared to be more effective than a larger one. Most of the people in the trial received a placebo or the regimen of two full doses, which was 62% effective. That group included people who were older than 55, Slaoui said.
The vaccine being developed with Oxford University was 90% effective when a half-dose was given before a full-dose booster, the partners said on Monday. However, that regime was administered to participants in a group whose age was capped at 55, Warp Speed’s Moncef Slaoui said Tuesday in a phone call with reporters.
Researchers have been puzzling about the AstraZeneca report since it was released, wondering why a smaller dose of the vaccine might have appeared to be more effective than a larger one. Most of the people in the trial received a placebo or the regimen of two full doses, which was 62% effective. That group included people who were older than 55, Slaoui said.
― Advanced Doomscroller (Sanpaku), Wednesday, 25 November 2020 18:16 (three years ago) link
jfc
― 𝔠𝔞𝔢𝔨 (caek), Wednesday, 25 November 2020 18:21 (three years ago) link
Britain’s best brains are on it 🇬🇧
― Gab B. Nebsit (wins), Wednesday, 25 November 2020 18:22 (three years ago) link
Oops.
― nickn, Wednesday, 25 November 2020 18:22 (three years ago) link
https://www.theguardian.com/world/2020/nov/25/culled-mink-rise-from-the-dead-denmark-coronavirus
― pomenitul, Wednesday, 25 November 2020 20:26 (three years ago) link
mmmm delicious
― early-Woolf semantic prosody (Hadrian VIII), Wednesday, 25 November 2020 20:27 (three years ago) link
astra zentake-a minute to check your work willya??
― Li'l Brexit (Tracer Hand), Wednesday, 25 November 2020 22:38 (three years ago) link
lol
― fleet doxes (map), Wednesday, 25 November 2020 22:54 (three years ago) link
astra not-zen eca
― fleet doxes (map), Wednesday, 25 November 2020 22:55 (three years ago) link
disastrazeneca
― gabbnebulous (Ye Mad Puffin), Wednesday, 25 November 2020 23:09 (three years ago) link
Re the UK, was startled to read that at least one testing site required you to go along and then ineptly do the nasal swab ON YOURSELF while a soldier watched from behind a protective window. The person who did this was understandably not confident when they got a negative test result.https://www.lrb.co.uk/blog/2020/november/in-liverpool
― Tsar Bombadil (James Morrison), Wednesday, 25 November 2020 23:12 (three years ago) link
JFC that is insane
― howls of non-specificity (sleeve), Wednesday, 25 November 2020 23:12 (three years ago) link
I think that's par for the course (apart from the soldier) I went for a test (literally at the end of my street!) and I had to do it myself.
― ILXceptionalism (Tom D.), Wednesday, 25 November 2020 23:15 (three years ago) link
I assume it's the same at every testing centre in the UK.
The site was being run by a bunch of enthusiastic young people who looked like they'd just be plucked off the local streets.
― ILXceptionalism (Tom D.), Wednesday, 25 November 2020 23:20 (three years ago) link
https://www.nytimes.com/2020/11/25/business/coronavirus-vaccine-astrazeneca-oxford.html
what a mess
― 𝔠𝔞𝔢𝔨 (caek), Wednesday, 25 November 2020 23:34 (three years ago) link
I don't think any of this is getting reported in the UK btw, certainly not on the BBC, the Tories have put all their eggs in the Astra-Zeneca basket and it's being portrayed everywhere as a great triumph for British science and ingenuity.
― ILXceptionalism (Tom D.), Wednesday, 25 November 2020 23:39 (three years ago) link
Basking in the results on Monday, Mr. Johnson said the vaccine “has the makings of a wonderful British scientific achievement.”
haha
― 𝔠𝔞𝔢𝔨 (caek), Wednesday, 25 November 2020 23:46 (three years ago) link
like Brexit, and the Garden Bridge, and, and,
― Li'l Brexit (Tracer Hand), Thursday, 26 November 2020 00:14 (three years ago) link
― ILXceptionalism (Tom D.), Wednesday, November 25, 2020 11:15 PM (yesterday) bookmarkflaglink
― ILXceptionalism (Tom D.), Wednesday, November 25, 2020 11:20 PM (yesterday) bookmarkflaglink
We had an option for them to do the test on us the first time we got tested - they did the test on me and my partner and then we tested our 6yo daughter. My partner got tested again a few weeks back and had to administer the test herself - she was going to care for her dad, who was having an operation - and was definitely anxious that she hadn't administered the test properly and would get a false-negative.
― Change Display Name: (stevie), Thursday, 26 November 2020 08:56 (three years ago) link
LOL misread that as your 6yo daughter had to administer the test herself. Nothing would surprise me tbh.
― ILXceptionalism (Tom D.), Thursday, 26 November 2020 09:14 (three years ago) link
https://pbs.twimg.com/media/EnvK99kXUAAvEJM?format=jpg&name=medium
good morning
― calzino, Thursday, 26 November 2020 09:20 (three years ago) link
Now we've got mink zombies to deal with.
― ILXceptionalism (Tom D.), Thursday, 26 November 2020 09:27 (three years ago) link
i believe you’ll find they prefer the term “nosfurrati”
― Li'l Brexit (Tracer Hand), Thursday, 26 November 2020 09:30 (three years ago) link
I wonder if PETA would have any issues about how various government agencies across Europe are treating undead furry lil' bastards!
― calzino, Thursday, 26 November 2020 09:35 (three years ago) link
(xp) Nosferretu surely?
― ILXceptionalism (Tom D.), Thursday, 26 November 2020 09:38 (three years ago) link
well if you’re using the singular
― Li'l Brexit (Tracer Hand), Thursday, 26 November 2020 09:43 (three years ago) link
Will read this later.
It pains me to say this, but... I think the claims made for the Oxford/AstraZeneca Covid-19 vaccine are on *very* shaky ground. We should wait for a solid large trial. My latest @WIRED https://t.co/BKJfaQS1nc With a timeline & extra sources here: https://t.co/ZaeheAgtEP— Hilda Bastian (@hildabast) November 25, 2020
― xyzzzz__, Thursday, 26 November 2020 09:59 (three years ago) link
I almost projectile vomited when they did me, because I am a wuss. She would probably have done a better job!
― Change Display Name: (stevie), Thursday, 26 November 2020 10:00 (three years ago) link
I would not be able to do it myself. That’s hard.
― All cars are bad (Euler), Thursday, 26 November 2020 10:03 (three years ago) link
The tonsil scrape is a nightmare.
― ILXceptionalism (Tom D.), Thursday, 26 November 2020 10:03 (three years ago) link
That's why, when they show footage of a test being administered on TV (which they do like clockwork), they always show the swab up the nose.
― ILXceptionalism (Tom D.), Thursday, 26 November 2020 10:07 (three years ago) link
The nose bit ain't fun either. When they administered the nose swab, the woman had to say, 'Sir, could you stop scrunching up your face, we can't get the swab far enough in.'
I'm a wuss, is what I'm saying.
― Change Display Name: (stevie), Thursday, 26 November 2020 10:16 (three years ago) link
I've only had the nose poke. Going that far back feels unnatural and I would surely not be able to force myself to do it.
― All cars are bad (Euler), Thursday, 26 November 2020 10:44 (three years ago) link
I've done my own test several times now, I feel fairly confident, except about how far up the nose I'm going
― kinder, Thursday, 26 November 2020 11:18 (three years ago) link
I'm just going to post that the SCOTUS ruling that came late last night is one of the most infuriating things I've ever encountered, and I'm angry quite a lot.
― healthy cocaine off perfect butts (the table is the table), Thursday, 26 November 2020 12:28 (three years ago) link
Yes... this is very, very bad. https://www.nytimes.com/2020/11/26/us/supreme-court-coronavirus-religion-new-york.html
We just had a secret wedding in Brooklyn with 7000 people so this is just wonderful, can only imagine how Christmas mass will add to the death tolls.
― Nhex, Thursday, 26 November 2020 16:34 (three years ago) link
hahaha well at least that won't impact my life oh wait that's walking distance hahaha no problem no problem
― the serious avant-garde universalist right now (forksclovetofu), Thursday, 26 November 2020 17:18 (three years ago) link
Yeah, all of the people on this board saying, "well if these wackos want to do it, fine whatever let them swim in covid" obviously don't know or care for people working on the front lines right now.
― healthy cocaine off perfect butts (the table is the table), Thursday, 26 November 2020 17:23 (three years ago) link
Like forks I am mere blocks from the nearest bk enclave so my deploration of this decision definitely includes some fear for my own safety
― covidsbundlertanze op. 6 (Jon not Jon), Thursday, 26 November 2020 17:38 (three years ago) link
I just got off the phone with my sister, who is an RN/MBA and hospital administrator at Stanford University Medical Center.
She is on Stanford's vaccine task force, and says the vaccines are real, and will really be happening, within weeks.
They are getting the Pfizer vaccine and it will go first to ED and ICU staff, then to COVID unit staff, then to high-risk patients. After that, ina manner to be determined, to normal people.
She said that even a couple weeks ago she would have been incredulous - said that two weeks ago she would have said it was a year away.
So that's potentially hopeful, maybe?
― gabbnebulous (Ye Mad Puffin), Thursday, 26 November 2020 17:50 (three years ago) link
Yes, it is hopeful news and should not be discounted.
The vaccine will certainly ease some of the emotional burden of nurses, doctors and other frontline workers, but the work will still be emotionally exhausting as they continue to see patient after patient suffering, often dying, the standard of care dropping as medical attention and equipment become triaged, and there is no vaccine available for their families and other loved ones. These people are having their hearts gouged at on a daily basis.
― Respectfully Yours, (Aimless), Thursday, 26 November 2020 18:12 (three years ago) link
I can see giving them to ICU people first, but I don’t agree with the plan to give them to people with erectile dysfunction at the same time.
― 𝔠𝔞𝔢𝔨 (caek), Thursday, 26 November 2020 18:13 (three years ago) link
Heh, I couldn't figure that out either.
― Robert Gotopieces (James Redd and the Blecchs), Thursday, 26 November 2020 18:19 (three years ago) link
It's the only way Trump could insure he got his dose first.
― ILXceptionalism (Tom D.), Thursday, 26 November 2020 18:23 (three years ago) link
Thanks to television, no one has yet caught up with ERs becoming EDs.
― Respectfully Yours, (Aimless), Thursday, 26 November 2020 18:24 (three years ago) link
That is great news, YMP! Giving thanks for that today.
― DJI, Thursday, 26 November 2020 18:44 (three years ago) link
― Two Meter Peter (Ste), Thursday, 26 November 2020 19:28 (three years ago) link
Emergency DEPARTMENT, sheesh
But you knew that
― gabbnebulous (Ye Mad Puffin), Thursday, 26 November 2020 21:22 (three years ago) link
I'm worried about those orthodox hats catching a mutated form of the virus.
― the colour out of space (is the place) (PBKR), Friday, 27 November 2020 14:20 (three years ago) link